On the 26th and 27th of August 2025, the Cascading Climate and Health Risks in African Cities (CASCADE) team held the 2nd Accra City Learning Lab at the Centre for Climate Change and Sustainability Studies, University of Ghana. Every year, the CASCADE team brings together partners and stakeholders from South Africa (Johannesburg and Cape Town), Ghana (Accra), Uganda (Kampala), and Zimbabwe (Harare) to share knowledge and co-create solutions addressing climate change-related issues in these cities. Around September last year (2024), the CASCADE team held Accra’s first City Learning Lab, welcoming colleagues from across Africa and key stakeholders in Ghana, including Metropolitan, Municipal, and District Assemblies (MMDAs), the Environmental Protection Authority (EPA), the National Disaster Management Organization (NADMO), and the Ghana Meteorological Agency (GMet).