We examined the gastro-intestinal tracts (guts) of 160 fish species obtained from Nigerian coastal waters for microplastics and estimated annual microplastic intake by adult human population in the region from the fish species. A total of 5744 microplastics were recovered from the fish species analyzed with an average of 39.65 ± 5.67 items/individual. Microbeads (43%) occurred in all guts assessed, followed by fragments (27%), burnt film (14%), thread (9%), fibers (4%), and pellets (3%). Most microplastics recovered were below 1000 μm with the least size being 85 μm.